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Gut Health
because 'it's just stress' isn't a diagnosis.

Intestinal permeability (zonulin), gut inflammation (calprotectin), secretory IgA, microbiome diversity and short-chain fatty acid output. A read on what your gut lining and flora are actually doing - beyond the IBS label.

$149
Flat price · HSA/FSA
Results in 7–10 days
Turnaround
At-home stool sample · collection supplies at your lab visit
Sample method
  • No insurance required
  • HSA & FSA eligible
  • CLIA-accredited labs
Why this panel

Women are more likely to be dismissed with an IBS label - calprotectin gives a yes/no on real inflammation.

Intestinal permeability is higher in women with endometriosis, autoimmune disease, and during estrogen drops. Calprotectin distinguishes inflammatory bowel disease from IBS; elevated zonulin quantifies the 'leaky gut' conversation.

~2×
Women are more likely to be diagnosed with IBS than men[1]
~70%
Of the immune system lives in the gut lining[2]
5–7 yrs
Average delay to IBD diagnosis in women with GI symptoms[3]
What we measure

The 58 biomarkers in this panel - and why each one.

Tap a marker to read the clinical note and the women-specific context.

Calprotectin

Gut Health

Stool calprotectin reflects neutrophil activity in the intestinal lining; the gold-standard non-invasive screen for intestinal inflammation.

Unit mcg/g
Optimal <50 mcg/g
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Zonulin

Gut Health

Zonulin regulates tight junctions between intestinal cells; elevated levels signal increased intestinal permeability.

Unit ng/mL
Optimal <30 ng/mL
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sIgA

Gut Health

Secretory IgA is the dominant antibody of mucosal immunity and the first line of defense in the gut lining.

Unit mg/dL
Optimal 51–204 mg/dL
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Microbiome Diversity Index

Gut Health

A composite score of gut bacterial species richness and evenness; higher diversity correlates with better metabolic and immune health.

Unit index (Shannon)
Optimal >3.5
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Short-Chain Fatty Acids

Gut Health

SCFAs produced by bacterial fermentation of dietary fiber feed colonocytes, reinforce the gut barrier, and regulate immune tone.

Unit mmol/kg
Optimal Butyrate >5 mmol/kg
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White Blood Cell Count

CBC with Differential

Total count of white blood cells; the front-line defense of the immune system.

Unit K/µL
Optimal 3.5–10.5 K/µL
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Red Blood Cell Count

CBC with Differential

Total red blood cell count; used alongside hemoglobin and hematocrit to assess anemia.

Unit M/µL
Optimal 3.9–5.0 M/µL
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Hemoglobin

CBC with Differential

The oxygen-carrying protein in red blood cells; the primary measure of anemia severity.

Unit g/dL
Optimal 12.0–16.0 g/dL
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Hematocrit

CBC with Differential

The fraction of blood volume occupied by red blood cells.

Unit %
Optimal 36–46%
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MCV

CBC with Differential

Mean corpuscular volume — the average size of red blood cells; elevated in B12/folate deficiency, low in iron deficiency.

Unit fL
Optimal 80–100 fL
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MCH

CBC with Differential

Mean corpuscular hemoglobin — the average amount of hemoglobin per red cell; low MCH is an early signal of iron depletion.

Unit pg
Optimal 27–33 pg
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MCHC

CBC with Differential

Mean corpuscular hemoglobin concentration — classic for iron-deficiency anemia when low.

Unit g/dL
Optimal 32–36 g/dL
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RDW

CBC with Differential

Red cell distribution width — measures variability in red cell size; elevated RDW reflects oxidative stress and mixed deficiencies.

Unit %
Optimal <14%
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Platelet Count

CBC with Differential

The circulating particles that initiate clotting; low counts increase bleeding risk, high counts can reflect inflammation or iron deficiency.

Unit K/µL
Optimal 150–400 K/µL
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MPV

CBC with Differential

Mean platelet volume — larger platelets are more reactive; elevated MPV is associated with cardiovascular and thrombotic risk.

Unit fL
Optimal 7.5–12.5 fL
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Absolute Neutrophils

CBC with Differential

Absolute count of neutrophils — the first responders to bacterial infection.

Unit K/µL
Optimal 1.8–7.7 K/µL
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Absolute Band Neutrophils

CBC with Differential

Immature neutrophils (bands) — elevated counts (left shift) indicate acute bacterial infection or bone marrow stress.

Unit K/µL
Optimal 0–0.7 K/µL
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Absolute Metamyelocytes

CBC with Differential

Immature granulocyte precursors; presence in blood indicates bone marrow stress or severe infection.

Unit K/µL
Optimal 0 K/µL
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Absolute Myelocytes

CBC with Differential

Granulocyte precursors; circulating myelocytes indicate abnormal bone marrow release.

Unit K/µL
Optimal 0 K/µL
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Absolute Promyelocytes

CBC with Differential

Very early granulocyte precursors; their presence in blood is abnormal and requires urgent evaluation.

Unit K/µL
Optimal 0 K/µL
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Absolute Lymphocytes

CBC with Differential

Absolute count of lymphocytes — key mediators of adaptive immunity including T and B cells.

Unit K/µL
Optimal 1.0–4.8 K/µL
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Absolute Monocytes

CBC with Differential

Absolute monocytes; these differentiate into macrophages and dendritic cells in tissue.

Unit K/µL
Optimal 0.2–0.95 K/µL
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Absolute Eosinophils

CBC with Differential

Absolute eosinophils; respond to allergic reactions and parasitic infections.

Unit K/µL
Optimal 0.05–0.5 K/µL
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Absolute Basophils

CBC with Differential

Absolute basophils — the rarest white cell, involved in allergic and inflammatory responses.

Unit K/µL
Optimal 0–0.1 K/µL
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Absolute Blasts

CBC with Differential

Blast cells in peripheral blood; any presence is abnormal and requires immediate haematology referral.

Unit K/µL
Optimal 0 K/µL
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Absolute Nucleated RBC

CBC with Differential

Nucleated red blood cells in peripheral blood; normally only present in foetal circulation and severe anaemia.

Unit K/µL
Optimal 0 K/µL
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Neutrophils %

CBC with Differential

Percentage of neutrophils in the white cell differential; elevated in bacterial infection and stress.

Unit %
Optimal 40–74%
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Band Neutrophils %

CBC with Differential

Percentage of band (immature) neutrophils; elevated in acute bacterial infection.

Unit %
Optimal 0–7%
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Metamyelocytes %

CBC with Differential

Percentage of metamyelocytes; should be absent from normal peripheral blood.

Unit %
Optimal 0%
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Myelocytes %

CBC with Differential

Percentage of myelocytes; absent from normal blood.

Unit %
Optimal 0%
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Promyelocytes %

CBC with Differential

Percentage of promyelocytes; absent from normal blood.

Unit %
Optimal 0%
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Lymphocytes %

CBC with Differential

Percentage of lymphocytes in the white cell differential; reflects adaptive immunity.

Unit %
Optimal 20–44%
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Reactive Lymphocytes %

CBC with Differential

Atypical (reactive) lymphocytes; elevated in viral infections such as EBV and CMV.

Unit %
Optimal 0–5%
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Monocytes %

CBC with Differential

Percentage of monocytes; elevated in chronic infections and inflammatory conditions.

Unit %
Optimal 4–11%
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Eosinophils %

CBC with Differential

Percentage of eosinophils; elevated in allergic and parasitic conditions.

Unit %
Optimal 0–5%
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Basophils %

CBC with Differential

Percentage of basophils; mildly elevated counts can accompany allergic inflammation or thyroid disease.

Unit %
Optimal 0–1%
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Blasts %

CBC with Differential

Percentage of blasts; absent from normal blood. Any presence requires urgent evaluation.

Unit %
Optimal 0%
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Nucleated RBC %

CBC with Differential

Nucleated RBCs per 100 WBCs; should be absent in normal adults.

Unit per 100 WBC
Optimal 0
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CBC Comment

CBC with Differential

Pathologist or automated comment on peripheral blood findings.

Unit
Optimal
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Glucose

Comprehensive Metabolic Panel

Fasting serum glucose — the primary screen for diabetes and metabolic dysfunction.

Unit mg/dL
Optimal 70–99 mg/dL (fasting)
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Urea Nitrogen (BUN)

Comprehensive Metabolic Panel

Blood urea nitrogen — a kidney filtration marker; elevated with dehydration or renal impairment.

Unit mg/dL
Optimal 7–20 mg/dL
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Creatinine

Comprehensive Metabolic Panel

Muscle waste product filtered by the kidneys; used to estimate GFR.

Unit mg/dL
Optimal 0.5–0.9 mg/dL
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eGFR

Comprehensive Metabolic Panel

Estimated glomerular filtration rate — the best single-number indicator of kidney function, calculated from creatinine using CKD-EPI.

Unit mL/min/1.73m²
Optimal >60 mL/min/1.73m²
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BUN/Creatinine Ratio

Comprehensive Metabolic Panel

The ratio of BUN to creatinine; helps distinguish pre-renal from intrinsic kidney causes of elevated BUN.

Unit ratio
Optimal 10–20
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Sodium

Comprehensive Metabolic Panel

Primary extracellular cation; regulates fluid balance and nerve/muscle function.

Unit mEq/L
Optimal 136–145 mEq/L
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Potassium

Comprehensive Metabolic Panel

Primary intracellular cation; critical for heart rhythm, muscle contraction, and nerve signalling.

Unit mEq/L
Optimal 3.5–5.0 mEq/L
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Chloride

Comprehensive Metabolic Panel

The main anion that balances sodium; used to evaluate acid-base and electrolyte status.

Unit mEq/L
Optimal 98–107 mEq/L
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Carbon Dioxide (CO₂)

Comprehensive Metabolic Panel

Serum bicarbonate reflecting the body's acid-base reserve; low values can indicate metabolic acidosis.

Unit mEq/L
Optimal 22–29 mEq/L
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Calcium

Comprehensive Metabolic Panel

Total serum calcium; critical for bone density, muscle contraction, and nerve signalling.

Unit mg/dL
Optimal 8.5–10.2 mg/dL
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Protein, Total

Comprehensive Metabolic Panel

Total serum protein (albumin + globulins); reflects overall nutritional status and liver and immune function.

Unit g/dL
Optimal 6.0–8.3 g/dL
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Albumin

Comprehensive Metabolic Panel

The most abundant serum protein; reflects liver synthetic function, nutrition, and systemic inflammation.

Unit g/dL
Optimal 3.5–5.0 g/dL
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Globulin

Comprehensive Metabolic Panel

Calculated globulin fraction (total protein minus albumin); includes immunoglobulins, clotting factors, and transport proteins.

Unit g/dL
Optimal 2.0–3.5 g/dL
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Albumin/Globulin Ratio

Comprehensive Metabolic Panel

The A/G ratio; a low ratio (reversed) can indicate autoimmune disease, liver disease, or malignancy.

Unit ratio
Optimal >1.0
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Bilirubin, Total

Comprehensive Metabolic Panel

The breakdown product of haemoglobin; elevated in liver disease, haemolysis, or bile duct obstruction.

Unit mg/dL
Optimal 0.2–1.2 mg/dL
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Alkaline Phosphatase

Comprehensive Metabolic Panel

Enzyme produced in liver and bone; elevated in cholestasis, bone disease, and pregnancy.

Unit U/L
Optimal 30–100 U/L
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AST

Comprehensive Metabolic Panel

Aspartate aminotransferase — liver and muscle enzyme; elevated with hepatocellular damage or intense exercise.

Unit U/L
Optimal 10–35 U/L
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ALT

Comprehensive Metabolic Panel

Alanine aminotransferase — the most specific liver enzyme; elevated in hepatitis, fatty liver, and medication toxicity.

Unit U/L
Optimal 7–35 U/L
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hs-CRP

Inflammation

High-sensitivity C-reactive protein — the most sensitive blood measure of systemic low-grade inflammation.

Unit mg/L
Optimal <1.0 mg/L (low risk)
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Who this is for

Order this panel if any of these fit.

BloatingIBS symptomsFood sensitivities
  • 1You have chronic bloating, reflux or food sensitivities that keep expanding
  • 2You have an autoimmune condition (thyroid, skin, joints)
  • 3You've had recurrent antibiotics, or are post-antibiotic and not recovering
  • 4You have endometriosis or ongoing pelvic/abdominal pain
How it works

Three steps, no waiting room.

01
Order online

Choose your panel and complete a 2-minute intake. We schedule your lab visit or at-home phlebotomy appointment right after checkout.

02
Collect stool at home

Your collection supplies are handed off at your lab appointment or by your at-home phlebotomist. Take the sample privately at home and return it to your lab partner.

03
Get reviewed results

Results in 7–10 days - a plain-language report with research-backed ranges for women and flags on anything that warrants follow-up. Share with your own clinician for interpretation.

FAQ

Things people ask before ordering.

Calprotectin is a screening, not a replacement. A low calprotectin with matching symptoms strongly suggests IBS over IBD. A high result is a green light for GI referral and imaging.

Sources

Claims on this page are grounded in peer-reviewed research and society guidelines.

  1. [1]
    Lovell RM, Ford AC. Effect of gender on prevalence of IBS: systematic review and meta-analysis.
    Am J Gastroenterol, 2012
  2. [2]
    Vighi G et al. Allergy and the gastrointestinal system.
    Clin Exp Immunol, 2008
  3. [3]
    Pellino G et al. Sex- and Gender-Related Issues in IBD.
    J Crohns Colitis, 2023
  4. [4]
    Fasano A. Zonulin and Its Regulation of Intestinal Barrier Function.
    Physiol Rev, 2011

EllaDx panels are not a substitute for medical diagnosis. All results are reviewed by a licensed physician. Always consult a qualified clinician about changes to your care.

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